OVERVIEW
We are seeking a skilled professional to join a well-known client’s team as a Scientist III in Ridgefield, Connecticut. The Scientist III will support the development of protein biotherapeutics by leading purification and analytical efforts in a fast-paced research environment. This role will contribute directly to understanding protein attributes, stability, and function, making it a highly impactful opportunity within biologics discovery and development.
RESPONSIBILITIES
• Plan, coordinate, and execute purification of biotherapeutic proteins using chromatography techniques (Affinity, SEC, CEX, AEX, MMC, HIC)
• Troubleshoot complex purification systems and support process development efforts
• Perform analytical techniques to assess protein purity, stability, and quality (HPLC-SEC, SDS-PAGE, CGE, DLS)
• Design and conduct stage-appropriate purification and characterization studies to evaluate protein behavior under process conditions
• Analyze and interpret experimental and production data to understand physicochemical properties of proteins
• Develop and implement novel analytical methods and evaluate new technologies to enhance purification capabilities
• Identify and implement automation strategies and data analysis tools to improve data quality, throughput, and workflow efficiency
• Collaborate cross-functionally with research and development teams to support broader biotherapeutics discovery goals
• Present findings and scientific insights to internal stakeholders and project teams
• Maintain accurate documentation and ensure compliance with SOPs, safety, and regulatory requirements
• Support additional protein biochemistry and purification-related activities as needed
EXPERIENCE
Extensive hands-on experience in protein purification and analytical characterization required
Experience with chromatography-based purification methods and protein analytics required
Experience with data analysis, interpretation, and troubleshooting in a research environment required
Experience with automation, high-throughput workflows, or scripting preferred
Experience with mammalian cell culture and antibody expression systems preferred
Strong understanding of protein biochemistry and molecular biology principles required
EDUCATION
Master’s Degree with 3+ years of relevant experience OR
Bachelor’s Degree with 7+ years of relevant experience in Biochemistry, Bioengineering, Molecular Biology, or a related scientific discipline required
To be a best-fit your strengths must include:
• Strong expertise in protein purification and analytical characterization techniques
• Solid understanding of protein structure, stability, and biophysical properties
• Excellent problem-solving and troubleshooting skills in complex experimental systems
• Strong data analysis and interpretation capabilities
• Experience working in fast-paced, multi-project research environments
• High attention to detail and strong organizational skills
• Ability to collaborate effectively across cross-functional teams
• Strong written and verbal communication skills
• Proactive, self-motivated mindset with a focus on innovation and continuous improvement
Full-time employees are also eligible for benefits options such as health coverage, life insurance, disability insurance, and 401k benefits.
At Advanced Group, our commitment to diversity and inclusion in every part of our organization is crucial to fulfilling our mission and demonstrating our REAL values. Advanced Group is committed to providing employment opportunities without regard to sex, race, color, age, national origin, religion, gender identity or expression, sexual orientation or sexual preference, pregnancy or maternity, genetic information, marital status, disability, veteran status, or any other basis protected by applicable federal, state or local law.
Advanced Group complies with federal and state disability laws and makes reasonable accommodations for applicants and candidates with disabilities. If a reasonable accommodation is needed to participate in the job application or interview process, please contact [email protected].
#MSPTalent
#LI-NS1